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22 The most studied RNS, NO, is a membrane-soluble free radical that is synthesized by nitric oxide synthase (NOS)

Finally, enriched environments (e.g., socially, physically, and cognitively enriched) have been reported to upregulate the NRF2-ARE pathway in rats (Zhang et al., 2021)

Your note doesn't need a separate MDM summary section, but the elements must be identifiable

Moreover, M+3 labeling of cystathionine, cysteine, and glutathione was evident in homocysteine treated conditions, demonstrating active cysteine synthesis from serine