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Another randomized controlled trial assessed the effects of microencapsulated sodium butyrate (1.5 g/day for 12 weeks) in 52 patients with type 2 diabetes mellitus (T2DM) and abdominal pain

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Takahashi R, Kanda T, Komatsu M, Itoh T, Minakuchi H, Urai H, Kuroita T, Shigaki S, Tsukamoto T, Higuchi N, Ikeda M, Yamanaka R, Yoshimura N, Ono T, Yukioka H, Hasegawa K, Tokuyama H, Wakino S, Itoh H (2022) The significance of NAD + metabolites and nicotinamide N -methyltransferase in chronic kidney disease