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doi: 10.3892/mmr.2021.12416 141 LiG.ZhouJ.WeiJ.LiuB

LZ: Writing original draft, Writing review and editing, Conceptualization, Data curation, Formal Analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization

Mechanisms of Actions of Curcumin in Kidney Disease Curcumin exerts pleiotropic actions targeting oxidative stress, inflammation, apoptosis, endoplasmic reticulum (ER) stress, fibrosis, and metabolic dysregulation [64,65] (Table 2 and Figure 3)

Some patients may not be appropriate candidates based on active conditions, medication use, or other medical factors