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Intestinal glandular epithelial cells in Crohns disease and ulcerative colitis express abundant PLA2G2A, whereas inflammatory cells lack this protein

Once the tyrosinase process has been inhibited the metabolic pathway then turn its course going to the synthesis of light pigmented melanin called Phaeomelanin instead of synthesizing dark pigmented melanin called Eumelanin

Machine-learning-based prediction models that integrate clinical characteristics, laboratory parameters, and multi-omic data have demonstrated superior performance in forecasting clinical outcomes such as disease relapse, therapeutic response, and hospitalization risk

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