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Technol ., 6: 914-919

Oxidative stress can even cause visible changes on your skin, showing up as fine lines and wrinkles

In a clinical trial (NCT01834989), IGF-1 was locally infused to improve the tendon structure in patients with patellar tendinopathy, but the overall results indicated no therapeutic benefit for tendon healing associated with local IGF-1 injection [444]

Arch Neurol 66:11061113 Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, Korell M, Marras C, Bhudhikanok GS, Kasten M, Chade AR, Comyns K, Richards MB, Meng C, Priestley B, Fernandez HH, Cambi F, Umbach DM, Blair A, Sandler DP, Langston JW (2011) Rotenone, paraquat, and Parkinsons disease