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STAT5b in human subjects is critical for GH-induced IGF-I expression and growth promotion as demonstrated by the identification of mutations in the STAT5b gene of patients presenting with severe GH insensitivity in the presence of normal GHR (58)

Although GSH and vitamin C show partial functional redundancy under oxidative stress, their combined presence provides maximal protection against lipid hydroperoxides

It is shorter acting and more relevant to research models focused on transient GHRH receptor activation