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Chem Res Toxicol 21:213447 Siems W, Crifo C, Capuozzo E, Uchida K, Grune T, Salerno C (2010) Metabolism of 4-hydroxy-2-nonenal in human polymorphonuclear leukocytes

Mndez, C., Gonzlez-Sabn, J., Mors, F

However, ammonoptosis remains an emerging concept, and whether it represents a distinct and broadly conserved form of regulated T-cell death, or rather a context-specific consequence of ammonia-induced organellar stress, requires further validation across tumor types and immune-cell states