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Patients with persistent symptoms who develop polyarthritis with an abnormal joint exam suggestive of rheumatoid arthritis or psoriatic arthritis following treatment for acute Lyme disease have also been described (97)

To this end, the purified protein was dialyzed against 10 mM ammonium acetate pH 6.6, followed by the addition of 50 % (v/v) methanol and 1 % (v/v) formic acid, and directly applied via a syringe pump at 90 L/h