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Moreover, the expression of TXNIP is required for the VEGF-mediated VEGFR2 activation and angiogenic response in vivo and in vitro by regulating VEGFR2 phosphorylation via S -glutathionylation of the low molecular weight protein tyrosine phosphatase (LMW-PTP) in endothelial cells [150]

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Heavy drinking carries the same risks as binge drinking