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DOWNLOAD OUR SUPPLEMENT SAFETY GUIDE For a substance or method to be added to the List, it must meet at least two of the following three criteria: For athletes who require a prohibited substance or method but have a legitimate medical reason, they can apply for a Therapeutic Use Exemption (TUE) to meet the criteria outlined in the International Standard for Therapeutic Use Exemptions (ISTUE)

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1,2,6 Neurologic manifestations are caused by progressive demyelination and can include peripheral neuropathy, areflexia, and the loss of proprioception and vibratory sense