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Proline derived from these collagens is converted into glutamate and -KG by proline oxidase (PRODH1), which helps maintain the TCA cycle and provides precursors for biosynthesis [175]

Baez-Mendoza, R

The term "humanized immunoglobulin chain" or "humanized antibody chain" (i.e., a "humanized immunoglobulin light chain" or "humanized immunoglobulin heavy chain") refers to an immunoglobulin or antibody chain (i.e., a light or heavy chain, respectively) having a variable region that includes a variable framework region substantially from a human immunoglobulin or antibody and complementarity determining regions (CDRs) (e.g., at least one CDR, preferably two CDRs, more preferably three CDRs) substantially from a non-human immunoglobulin or antibody, and further includes constant regions (e.g., at least one constant region or portion thereof, in the case of a light chain, and preferably three constant regions in the case of a heavy chain)

f , Volcano plot showing relative fold change (log 2 ) in IP protein abundance versus log 10 (adjusted P value) from HEK293T cells expressing ER-tag compared to those expressing control-tag (n = 3, P-value adjusted for 1% permutation-based FDR correction)