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A quasi-experiment to study the impact of vancomycin area under the concentration-time curve-guided dosing on vancomycin-associated nephrotoxicity

J Pharmaceutical Sciences 104(9): 3170-3182

Intuitively, you should expect that binding will increase, especially as L gets greater

These findings support the concept that the microbiota indirectly modulates -cell subpopulations through the adipose tissueinflammationinsulin resistance and SCFA/LPSincretins-cells axes, even though direct single-cell studies demonstrating differential responses of individual -cell subtypes to microbiota-derived metabolites are not yet available (Doumatey et al., 2020)