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*Correspondence: Xin Yao, [email protected] This article was submitted to Autoimmune and Autoinflammatory Disorders, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

[1] Their limitation is that they associate variants with a measured trait usually total serum B12 and cannot tell whether the change reflects the active fraction or a mere reservoir shift, nor whether any intervention (let alone a specific form) would change an outcome

For others, their system may need a more regular top-up to maintain optimal levels

If you experience a power outage or the medication was inadvertently left unrefrigerated, contact your pharmacy for guidance on whether the product remains safe to use