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Key Regulatory Points as of 2026: Not FDA-approved for any medical indication Cannot legally be sold as a drug, food, or dietary supplement for human consumption Legally sold as a "research chemical," not intended for human use Not a DEA-scheduled substance, so possession is not illegal (unlike anabolic steroids) Many medical clinics offer BPC-157 treatments despite lack of approval The FDA has expressed safety concerns due to the lack of human clinical trial data and the potential for adverse effects from unregulated manufacturing

Also, due to limited quantity of samples, in a few cases the measurement of certain compounds had only one technical replicate instead of two (as indicated in Source data) because there were insufficient samples to inject twice in both LCMS methods covering the measurement of all compounds

SARS-CoV-2 infection causes GSH deficiency in the body through inhibition of nuclear factor erythroid 2related factor 2 ( Nrf2 ) pathway, the up-regulator of GSH synthesis 593