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In these individuals, use of anti-neoplastic agents should be considered early

More recent studies describe apoptosis as a regulator of cell fate, determining which cells should be eliminated due to DNA mutations or other proteins malfunctions and which cells should be preserved to maintain homeostasis

As NAD+ decreases, we see metabolic results like nutrient deficiencies and obesity, causing diabetes and high blood pressure, age related diseases, and cognitive decline

The clinical manifestations of patients with fatigue vary and may be related to factors such as the cause, course of disease and comorbidities of fatigue