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UroA also has anticancer properties and has been shown to regulate the expression of multiple genes involved in oncogenesis, cell cycle regulation, tumor suppression, and growth factor signaling [23, 29,30,31]

Similarly, Ephrin A5, a development-associated growth inhibitor, is upregulated in astrocytes after ischemic stroke (Overman et al., 2012), and local inhibition of Ephrin A5 signaling in the sub-acute phase promotes axonal growth and functional recovery (Overman et al., 2012)

Notably, plants and animals exhibit significant differences in the hierarchical action of LLPS within RCD pathways