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Finally, in an ex vivo retinal culture model for oxidative injury induced by hydrogen peroxide, a dose-dependent increase in microglia and elevation of CD11b expression was observed followed oxidative stress induction, with a time-dependent increase in IL-1 beta, iNOS, HSP70 at day 3 and TNF alpha and IL-1 beta at day 8 (Maliha et al., 2019)