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[64], NAC can rescue cells from bortezomib-induced peripheral neuropathy (BIPN), and delayed administration of these agents could achieve neuroprotection

Brain Res 2011

Environ Health Perspect 64:253257 Ross D, Norbeck K, Moldeus P (1985) The generation and subsequent fate of glutathionyl radicals in biological systems

The above evidence indicates that ferroptosis is the main way of DON-induced granulosa cell damage, and the use of ferroptosis inhibitor Fer-1 can improve DON-induced oxidative damage, enhance cell and mitochondrial activity, and improve cell function