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Precaution should be taken by individuals who are pregnant or breastfeeding, as it is unknown whether this drug may cause fetal or infant harm

FIGURE 2 Although TCA cycle is at the nexus of both catabolic and anabolic metabolism involving different key fuel molecules and metabolites, it was recently reported that alteration of amino acid metabolism is the main consequence of TCA cycle disruption (Ryan et al., 2021)

Therefore, in the absence of claims data, we proposed to continue to use our equitable adjustment authority under section 1833(t)(2)(E) of the Act to maintain the CY 2025 payment rate of $4.69 per mm 2 for HCPCS code C2645, which we proposed to be assigned to APC 2648 (Brachytx planar, p-103), for CY 2026

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