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The mean change from baseline and across sessions in success rate in achieving rewards through effort exertion was used to evaluate changes in objective motivation

In that study, children with ASD were administered a thiamine derivative, bi-daily for 2 months and noted improved communication skills, sociability, sensory/cognitive awareness, and behavior in 8 out of the 10 children studied as well as reduction in urine arsenic and mercury levels (149)

S -(1,2-Dichlorovinyl)-L-cysteine sulfoxide, however, was significantly more nephrotoxic than S -(1,2-dichlorovinyl)-L-cysteine at equivalent doses (Lash et al