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Plesiomonas and Cetobacterium were dominant in both the mucosa- and digesta-associated microbiota of freshwater-acclimated fish while pathogenic Vibrio , Staphylococcus , and Acinetobacter genera were dominant in the saltwater group

However, these findings were not statistically significant ( p =0.546)

As a result, the Western diet reduces testosterone levels leading to a decrease in sperm count, motility and morphology

consequently, reduced or temporally/spatially mismatched Treg-derived cytokines (TGF-, IL-10, and IL-35) can weaken mucosal tolerance and reparative programs, whereas context-dependent Treg overexpansion may impair antimicrobial immunity, resulting in dysregulated intestinal homeostasis 50,51