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Antisense and Ribozyme (Antagonists) In specific embodiments, antagonists according to the present invention are nucleic acids corresponding to the sequences contained in SEQ ID NO:1, or the complementary strand thereof, and/or to nucleotide sequences contained a deposited clone

4.2 Psoriasis Psoriasis occurs as a result of a complex interaction between genetic and environmental factors causing DC activation to produce related cytokines such as IFN-, IFN-, IL-12, IL-23, IL-6, and TNF-

In the brains of patients with AD, microglia enhance intracellular copper accumulation by upregulating the copper transporter CTR1, triggering microglial cuproptosis