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The most frequently occurring adverse reactions (at least 1%) in all three groups were headache (5.5%, 5%, and 3.8%, respectively) and diarrhea (no difference among the three groups)

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For S9.6 antibody detection, the membrane was dried, UV-crosslinked (0.12 J/m), and after blocking in 5% (w/v) Skimmed Milk Powder (Coop, Switzerland) in TBS-T, incubated with mouse monoclonal S9.6 antibody (Kerafast, ENH001

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