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doi: 10.1038/s41574-019-0168-8 10

Sphingolipids are a heterogeneous family of lipids sharing the characteristic sphingoid base backbone: Sterols and isoprenoids, which form sterols, are an important group of lipids used as part of the cellular plasma membrane Plasma membrane A cell membrane (also known as the plasma membrane or plasmalemma) is a biological membrane that separates the cell contents from the outside environment

Gandaglia G, Salonia A, Passoni N, Montorsi P, Briganti A, Montorsi F

It does this by reducing global protein synthesis and enhancing gene expression targeted toward cellular recovery (chaperones, protein folding, etc.) [225, 226]