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Potential Unknown Side Effects: Although rare, side effects such as nausea, dizziness, or allergic reactions may occur, especially when not used under medical supervision

Infusions of blood or plasma should be monitored carefully to avoid precipitating pulmonary edema in elderly patients or patients with heart disease

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Other possible vitamin B12 shot side effects include: Headache Dizziness Rash Facial flushing Skin redness Cold symptoms Anxiety Swelling Diarrhea Vomiting High blood pressure How to Prevent The best way to avoid the potential side effects of too much vitamin B12 is to get the majority of your vitamin B12 from nutrient-rich food sources, including meat, poultry, seafood and dairy products