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People following a plant-based diet People whose diet is largely or wholly plant-based may require additional considerations to ensure their B12 intake is adequate

The first oncolytic HSV-1 armed with GM-CSF, talimogene laherparepvec (T-VEC), demonstrated significant anti-tumor efficacy leading to FDA and EMA approval for melanoma therapy (7173)

Published protocols Animal-model studies commonly report 10500 g/kg/day in rat models, administered intraperitoneally or subcutaneously over the experimental window