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In addition, immunohistochemistry analysis revealed no significant differences in GLUT1 and TXNIP protein levels in the ileum and colon of mice co-treated with metformin and STF-31 (Supplementary Fig

with any other drugs or solvents

Notably, the Galligan group recently reported that LGSH can undergo conversion to d-lactyl-CoA through a spontaneous S-to-S acyl transfer reactions, contributing to nonenzymatic lactylation (K d-la ) in GLO2-deficient cells 17