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doi:10.1016/j.progpolymsci.2021.101408 9

Augmented anticancer efficacy by si-RNA complexed drug-loaded mesoporous silica nanoparticles in lung cancer therapy

Several modifications have been made to mRNA display methods in order to address these limitations, including the use of cDNA display, 606,607 transcription-translation coupled with association of puromycin linker (TRAP) display, 608 cDNA TRAP display, 609 and click display

A phase 3 trial called REDEFINE-1 included over 3,400 people who were overweight or obese with one or more comorbidities (like hypertension or cardiovascular disease), but not type 2 diabetes