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3.2.1 Background BD is a chronic psychiatric condition characterized by alternating episodes of depression and elevated mood states, which may manifest as mania or hypomania

The copper concentration used in experiments critically influences cellular responses: low levels (0.10.1.2mmol/l) induce physiological/adaptive transcriptional changes, while higher levels (0.4-0.4.6mmol/l) trigger toxic, stress-related responses [24]

19 has also reported dendrite disruption in hippocampal CA1 region and behavioral disorders in neuron-specific GCL knockdown mouse

It is hypothesized that this action might be associated with increased activity of antioxidant enzymesproteins that help protect cells from damage due to oxidative stress