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The possible explanation for the increased spontaneous acrosome reaction as seen in this study could be due to inhibition of PKA, actin polymerisation or CAMKII and PLD pathways, which needs to be further interrogated

Cruzat V, Rogero MM, Keane KN, Curi R, Newsholme P (2018) Glutamine: metabolism and immune function, supplementation and clinical translation

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