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Tensiometry The investigation in separate groups of animals, includes measurement of ability to stretch (mm) carried out in separate experiments, immediately after sacrifice, at days 7, 14, 21, 42 by a special device Lineomat (MLW Medizinische Gerte, Chemnitz, Germany)

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No significant difference in overall survival was observed between patients who had taken IBRANCE plus letrozole and those who had taken letrozole plus placebo