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Description

Loops and layers of post-translational modifications of drug transporters

pointed out that LMP is presumably the result of Fe-mediated lysosomal ROS production and lysosomal membrane oxidation through the analysis of salinomycin-treated cells 6

Herein, we report the development and validation (Z 0.50) of a cell-based functional assay for high-throughput screening (HTS) of autoprocessing inhibitors using fusion precursors in combination with AlphaLISA (amplified luminescent proximity homogeneous assay ELISA)