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However, the longer-term KDp regimen appeared to have a greater protective impact, and a more impressive reduction of CCR2 content in AAA tissue

These genes code for a group of cytoprotective and antioxidant proteins that include multiple components of the thioredoxin pathway, antioxidant enzymes, i.e., NADPH quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO-1), and numerous enzymes that regulate glutathione biosynthesis and utilization (80)