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The pharmacological actions of M6G [90] might be of particular relevance, as indicated by their high efficacy at MOP located in the locus coeruleus [111], where opioid-induced long-term neuronal inhibition is an important contributor to the development of tolerance [232, 233]

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TAK1 negatively regulates NF-B and p38 MAP kinase activation in Gr-1+CD11b+ neutrophils

Thermogravimetric analysis (TGA) indicated that the decomposition temperature of CaT was between 180 and 210 C, and differential scanning calorimetry (DSC) revealed that the glass transition temperature ( T g ) of CaT was between 12 and 25 C (Figure S4 and S5)