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Description

However, in a subanalysis of patients with advanced adenoma at baseline (n=161), selenium supplementation reduced adenoma recurrence by 18% (88)

Selenium supplementation could increase GPX4 expression in T cells, thereby leading to an increase in Tfh cell numbers and improved antibody responses in vaccinated mice and young adults post-influenza vaccination (97)

In addition, ICI can lead to treatment-related toxicity

Theoretical Risks and Safety Nuance Preclinical Safety Observations While no major adverse events are reported in the limited human data, researchers note theoretical concerns based on animal models