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While pharmacokinetics interactions are mainly attributable to PAHs, nicotine does alter and possibly negate drug effects by activating the sympathetic nervous system (Lee et al., 1987

Park EY, Shimura N, Konishi T, Sauchi Y, Wada S, Aoi W, et al

Published online January 31, 2015 DOI: Abstract PDFPubReaderePub Biliopancreatic malignancies such as cholangiocarcinoma (CCA) has notoriously been diagnosed late