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Gastroenterology 148 , 10871106 (2015)

A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases

Clinical studies have documented that patients with group A -hemolytic streptococcal tonsillopharyngitis have a greater incidence of bacteriologic failure when treated with sulfamethoxazole and trimethoprim injection than do those patients treated with penicillin, as evidenced by failure to eradicate this organism from the tonsillopharyngeal area

In conclusion, the results from this preliminary crossover study suggest that the combination of hyaluronic acid and GSH-C4 is associated with improvements in symptoms and tear-film stability, together with reduced corneal staining in G-OSD, without altering tear volume