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This change triggers the endothelial cell apoptosis, vessel regression, and blood flow reduction in the CL ( 3 Epigenetic regulation of corpus luteum function In addition to genetic and signaling pathways, epigenetic mechanisms act as key integrators of hormonal and metabolic signals, ensuring coordinated regulation of corpus luteum function

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(2019) suggested that the graded expression of Dmrt factors repressing Pax6 transcription and thus establishing its lateral high /medial low expression gradient provides mediolateral positional information to cortical progenitors

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