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Baertling, F, Rodenburg, RJ, Schaper, J, Smeitink, JA, Koopman, WJH, Mayatepek, E, Morava, E, Distelmaier, F 2014, A guide to diagnosis and treatment of Leigh syndrome, Journal of Neurology, Neurosurgery & Psychiatry , vol

Interestingly, treatment withdrawal did not completely restore the mRNA transcripts, and a similar effect was observed for vitamin D metabolism genes and genes associated with NAFLD which was persistently higher, suggesting the epigenetic association between GSH deficiency and vitamin D metabolism genes