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Mol Psychiatry (2012) 17:290314.10.1038/mp.2010.136 32 CondieJGoldsteinJWainwrightMS

(For a full list of effects at different BACs, check the table under the BAC subsection 11.2.3 above.) Ethanol interacts with many drugs due to its widespread influences on different receptors and their pharmacological properties

Its withdrawal accelerates dopaminergic neuronal degeneration, weakening reward circuitry and impairs serotonin (5-HT) synthesis and reuptake, particularly during the night, contributing to vasomotor symptoms such as hot flashes and nocturnal sweats (58,59)