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A deficiency in B12 can lead to symptoms of depression, anxiety, and brain fog

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Heat-killed OP50-1 was produced by heating an overnight culture to 60 C for 30 min, prior to plate seeding

Bacteroidetes and some Negativicutes bacteria such as Veillonella , Dialister , synthesize propionate through succinate pathway (Anachad et al., 2023), and some Negativicutes bacteria via acrylate pathway, like Megasphaera elsdenii and Lachnospiraceae (Schoenfeld and Wojtczak, 2016), to generate propionate