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doi: 10.1016/j.biopsych.2017.11.018 60

They stated: "The 2-D method can be used for any breed, but direct extrapolation of our normal values should not be made to other breeds, because the heart has a slightly different appearance in various breeds reflecting variability in size, shape, and position within the thorax." The 2002 study's authors also were careful to exclude any findings comparing LA/Ao ratios of dogs with and without enlarged hearts