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Several significant GO terms in lung were related to an increased immune response and to an increase in genes contributing to the extracellular matrix (Fig

Subsequently, the available studies about these terms will be evaluated, highlighting the main findings/conclusions obtained and discerning their origin (preclinical or clinical)

In women with PCOS, circulating levels of inflammatory markers such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor- (TNF-) are significantly elevated (15)

For instance, composite nanofibers composed of gelatin, chitosan, collagen, or sodium alginate can be fabricated via electrospinning to create porous scaffolds that mimic the extracellular matrix, promoting cell adhesion and proliferation (e.g., spindle-shaped human dermal fibroblasts on gelatin/chitosan scaffolds) (Pezeshki-Modaress et al., 2018)