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Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12

When catalyzed by GST, the prodrug releases cytotoxic compounds

To gain a deeper understanding of how TST modulates the STAT3/GPX4 signaling pathway at the molecular level and subsequently influences ferroptosis, the researchers employed chromatin immunoprecipitation (ChIP) experiments