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Separately, intranasal administration of Lactobacillus casei CRL 431 has been shown to enhance the immune response to Streptococcus pneumoniae infection, as evidenced by increased levels of interleukin-10 (IL-10), interleukin-4 (IL-4), IgA, and TNF-in the respiratory tract (252)

Control, p .05, Table 1)

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After 2 week acute toxicity and cumulative tests in mice, no statistical difference existed between LAAM GSH-CQD group and normal control group in the parameters from complete blood count and serum biochemistry analyses (Supplementary Fig