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Conversely, the ferroptosis-resistant cell state, which is characterized by the upregulation of ferroptosis suppressors, epoxide hydrolases, phospholipases and by increased lipid metabolism (Fig

Konorov et al

Intriguing findings have been described in a chemotherapyinduced peripheral neuropathy model, as according to Kim and colleagues the mechanical threshold in paclitaxelinduced neuropathic pain has shown circadian oscillations in rats, with a minimal pain tolerance observed during the inactivity phase (daytime for rats)