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Tetrahedron Lett 11:38213824

These micelles showed synergistic effects and excellent anti-tumor efficacy in vitro and in vivo, proving a potential DDS for clinical applications [113]

Evidence from animal studies demonstrates that copper loading in rat hepatocytes leads to a significant increase in the mRNA expression of pyroptosis-related genes (caspase-1, IL-18, IL-1, and NLRP3) and the protein expression of caspase-1[111]