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Macedo LW, Cararo JH, Maravai SG et al (2016) Acute carnosine administration increases respiratory chain complexes and citric acid cycle enzyme activities in cerebral cortex of young rats

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Following NLRP3 inflammasome activation, caspase-1 cleaves pro-IL-1 and pro-IL-18 into their mature forms, releasing them into the extracellular space and exacerbating inflammatory damage