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NTBI can cross the plasma membrane and especially easily be absorbed by various cells, such as cardiomyocytes through calcium channels, causing cascade damage

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HYGIENE A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof A61K2800/88Two- or multipart kits AHUMAN NECESSITIES A61MEDICAL OR VETERINARY SCIENCE

and further comprising at least one excipient selected from the group consisting of: abrasives, carriers, sweeteners, flavorings, colorings, stabilizers, preservatives, viscosity enhancers, pH adjusters, buffers, sparkles, gelling agents, surfactants, effervescent agents, binders, thickeners, rheology modifying agents, remineralizing agents, humectants, desensitizing agents, sensitivity agents, whitening agents, mucosal adhesives, bad breath agents, gingivitis agents, astringents, and oxidizing agents