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Compared to a placebo, the occurrence of reactions decreased by 58.3%, as demonstrated by the Cox model

Nakano M, Murayama Y, Hu L, Ikemoto K, Uetake T, Sakatani K

[7] The scientists also commented, Very surprisingly, Ipamorelin did not [appear to] release ACTH or cortisol in levels significantly different from those observed following GHRH stimulation